Drug discovery strategies for acute radiation syndrome

Flexible Text Mining Strategies for Drug Discovery

The two text mining strategies: finding co-occurrences of biological entities within documents, and finding relationships using Natural Language Processing, are often seen as competitors. Here we adopt a flexible approach where the techniques are adapted and combined to suit the nature of the document corpus, and the specific task. The approach was tested on three tasks relevant to cancer treat...

Acute radiation syndrome and chronic radiation syndrome.

Acute radiation syndrome (ARS) or sickness or poisoning or toxicity is induced after a whole body exposure of men to high doses of radiation between 1-12Gy. First symptoms are from the gastrointestinal system, which together with bone marrow are the most sensitive parts of our body. Chronic radiation syndrome (CRS) may be induced by smaller than 1Gy radiation doses or after a mild form of ARS. ...

Ethnobotany, Ethnopharmacology and Drug Discovery

     This manuscript is a review of a number of ethnobotany and ethnopharmacology texts and papers in order to arrive at current understanding and scope of ethnobotany and ethnopharmacology. It includes either a brief definition of both fields and presenting some examples on them. Also it has a glimpse on the geographical coverage of research works throughout the world, important issue of prope...

Computational Strategies in Cancer Drug Discovery

Current Advances in Computational Strategies for Drug Discovery in Leishmaniasis

Andrés F. Flórez1,2, Stanley Watowich3 and Carlos Muskus2 1German Cancer Research Center (DKFZ)/ Division Theoretical Systems Biology, Heidelberg 2Universidad de Antioquia/Programa de Estudio y Control de Enfermedades Tropicales – PECET, Medellín 3University of Texas Medical Branch/Department of Biochemistry and Molecular Biology and the Sealy Center for Structural Biology and Molecular Biophys...